
01
Evidence first.
Our active ingredients are selected using published scientific evidence. Supporting references are provided for key ingredients.
Your cart
THE SCIENCE OF 2250
It is a combination.
Skin changes every month. Your routine shouldn't stay the same.
Scan your skin →THE STARTING POINT
Your skin is one of a kind.
Traditional labels such as dry, oily or combination describe only one part of your skin. They do not capture current visible concerns such as dehydration, redness, pores, uneven tone, texture or sensitivity.
He SY et al., JAAD 2014. Bailey EE et al., JAAD 2024.


Your skin changes with age, hormones, climate, and city. A fixed formula cannot keep up.

OUR ANSWER
Over 1,000 combinations. One personalized three-step routine.
Every 2250 product combines one selected Base with two targeted Pods. Across the complete Cleanser, Serum and Moisturizer routine, that means three selected Bases and six Pods. Many active ingredients can lose stability over time once incorporated into a finished formula. Our system keeps concentrated active blends separate in precisely dosed Pods until they are mixed into the Base at home.

HOW WE LEARN YOUR SKIN
One selfie. Our scan quantifies more than 10 visible skin signals, including tone, texture, pores, hydration, redness and pigmentation. From that, we build your personalized routine.
Liu Y et al., Nature Medicine 2020. Daneshjou R et al., Science Advances 2022.


Our scan is not a medical diagnosis. It is a guide to recommend the 2250 products that best match your skin today. If you have a medical condition, consult your dermatologist.
HOW WE CHOOSE INGREDIENTS
Uncompromising.
We move with it.
Cosmetic dermatology publishes hundreds of new studies every year, and we revisit our formulas every 12 months in light of new evidence. If something improves, we improve it. If something changes, we tell you.


your combination?
Your scan takes less than one minute.
Scan your skin →