THE SCIENCE OF 2250

Your skin is not a type

It is a combination.

That is why we do not believe in one product for everyone. We believe in personalized formulas, one for each skin.

THE STARTING POINT

Oily, dry, normal/combination

Three types for 8 billion skin types.

The scale dermatology uses to classify skin was invented in 1975. Even in studies with thousands of people, it classifies correctly only 9 out of 10 times — and leaves out almost everything that really matters: barrier function, sensitivity, sun response, aging behavior, and how skin reacts to each active.

He SY et al., JAAD 2014. Bailey EE et al., JAAD 2024.

Diverse group of people holding Cleanser Base, Serum Base, and Moisturizer Base bottles.
Diverse group of people holding Cleanser Base, Serum Base, and Moisturizer Base bottles.

Your skin changes with age, hormones, climate, and city. A fixed formula cannot keep up.

OUR ANSWER

1 Base + 2 Pods

More than 1,000 combinations.

We split your routine in two parts: one Base (Cleanser, Serum, or Moisturizer) that handles essentials, and two Pods that carry concentrated actives. Pods activate when mixed with your Base — fresh formula, made in the moment.

Cleanser Base bottle with two white concentrate pods on a black background.
HOW WE LEARN YOUR SKIN

Your skin in 60 seconds.

A selfie from your phone. Our technology reads signals the human eye cannot measure precisely: tone, texture, pores, hydration, redness, and signs of sun damage. From there, your combination is built.

Our scan is not a medical diagnosis. It is a guide to recommend the 2250 products that best match your skin today. If you have a medical condition, consult your dermatologist.

Liu Y et al., Nature Medicine 2020. Daneshjou R et al., Science Advances 2022.

Woman with glowing skin holding a yellow Moisturizer Base bottle.
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HOW WE CHOOSE INGREDIENTS

Five rules

No exceptions.

Evidence first.

01 —

Evidence first.

Every active in 2250 has published studies in reviewed dermatology journals. No 'trend ingredients' without backing.

Effective concentration.

02 —

Effective concentration.

An ingredient at too low a dose does not work. Each Pod carries its actives in the ranges where studies show real results.

Compatible across skin tones.

03 —

Compatible across skin tones.

We test that each formula works across diverse phototypes where skin reacts differently, and where many 'universal' products fail.

Barrier respect.

04 —

Barrier respect.

Results without destroying skin along the way. We prioritize actives that support barrier function while they work.

Full transparency.

05 —

Full transparency.

Complete INCI list, no fine print. If it is in the formula, it is on the box.

WHAT IS NEXT

Science always moves

We move with it.

Cosmetic dermatology publishes hundreds of new studies every year, and we revisit our formulas every 12 months in light of new evidence. If something improves, we improve it. If something changes, we tell you.

Close-up of skincare gel and cream textures on a warm beige background.